Punta de Manabique is a small peninsula that separates Amatique Bay from the Gulf of Honduras. It is located on Guatemala's east coast, some 20 km north of Puerto Barrios.
There is a rich diversity of molluscs, crustaceans, fishes, amphibians, reptiles (crocodile, green iguana, turtles). Many species of seabirds are found in the reserve, from the orders of Charadriiformes), Pelecaniformes, Ciconiiformes. Mammals include Baird's Tapir (Tapirus bairdii, jaguar (Panthera onca), howler monkey (Alouatta palliata), spider monkey (Ateles geoffroyi), collared Peccary (Tayassu tajacu) and white-lipped Peccary (Tayassu pecari).